Dentressangle Solidarité

Partnership with the Hospices Civils de Lyon

Dentressangle backs the hospices
civils de Lyon

Alongside the Hospices Civils de Lyon foundation, we support scientific and clinical research and therapy development in order to improve patients’ health and comfort, particularly in the field of organ transplants.
An unrivaled biocollection containing masses of information on transplantation.

Three hospital centers of excellence located in Paris, Lyon and Nantes perform joint research into transplantation focusing on kidney and pancreas transplants. Their mission is to raise awareness and mobilize resources to meet the challenges of life after transplantation.

3 questions for Prof. Emmanuel Morelon, Head of Transplantation, Nephrology and Clinical Immunology at Lyon’s Edouard Herriot hospital.

You conduct major research in the field of transplantation. Can you describe your work to us?

The transplantation, nephrology and clinical immunology department at Edouard Herriot hospital looks after all the medical aspects of kidney and pancreas transplantation as well as patients receiving composite grafts. Our aim is to meet the medical and scientific challenges associated with transplant rejection and to understand the side effects that degrade patients’ quality of life.

How is DENTRESSANGLE’s support important for transplant research?

We are working on patient biomarkers at all three of our centers in order to provide customized care. For this purpose, in 2012, thanks to DENTRESSANGLE’s support, we were able to compile an unparalleled biocollection containing millions of samples compared with clinical data. This data has enabled us to set up research programs to examine highly specific issues regarding transplantation.

What are the tangible results of this biocollection?

First, we were able to pinpoint and describe a new, previously unidentified type of rejection. Second, the research we conducted to understand pancreas transplant rejection allowed us to identify biological resources that have furthered our understanding of the role of antibodies. Lastly, we are currently developing a project called the I-Box. Based on the results obtained by our three centers, the I-Box will allow us to predict what will happen in the next ten years.